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Host Pathways Important for Coxiella burnetii Infection Revealed by Genome-Wide RNA Interference Screening

Coxiella burnetii is an intracellular pathogen that replicates within a lysosome-like vacuole. A Dot/Icm type IVB secretion system is used by C. burnetii to translocate effector proteins into the host cytosol that likely modulate host factor function. To identify host determinants required for C. bu...

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Detalhes bibliográficos
Main Authors: McDonough, Justin A., Newton, Hayley J., Klum, Scott, Swiss, Rachel, Agaisse, Hervé, Roy, Craig R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3560531/
https://ncbi.nlm.nih.gov/pubmed/23362322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00606-12
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