Prostate-targeted mTOR-shRNA inhibit prostate cancer cell growth in human tumor xenografts

Objective: To construct a recombinant lentivirus vector driven by the PSMA promoter carrying mTOR-shRNA, and to obtain the effect on the mTOR gene silencing in human prostate cancer xenografts. Methods: The complimentary oligos of small interference RNA (siRNA) with hairpin structures targeting the...

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Autors principals: Du, Yue-Feng, Long, Qing-Zhi, Shi, Ying, Liu, Xiao-Gang, Li, Xu-Dong, Zeng, Jin, Gong, Yong-Guang, Wang, Xin-Yang, He, Da-Lin
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2013
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3560496/
https://ncbi.nlm.nih.gov/pubmed/23386916
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