Beta-amyloid toxicity modifier genes and the risk of Alzheimer’s disease

Late-onset Alzheimer’s disease (LOAD) is a complex and multifactorial disease. So far ten loci have been identified for LOAD, including APOE, PICALM, CLU, BIN1, CD2AP, CR1, CD33, EPHA1, ABCA7, and MS4A4A/MS4A6E, but they explain about 50% of the genetic risk and thus additional risk genes need to be...

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Autors principals: Rosenthal, Samantha L, Wang, Xingbin, Demirci, F Yesim, Barmada, Michael M, Ganguli, Mary, Lopez, Oscar L, Kamboh, M Ilyas
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2012
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3560458/
https://ncbi.nlm.nih.gov/pubmed/22984654
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