Modeling of lamin A/C mutation premature cardiac aging using patient-specific induced pluripotent stem cells

AIMS: We identified an autosomal dominant non-sense mutation (R225X) in exon 4 of the lamin A/C (LMNA) gene in a Chinese family spanning 3 generations with familial dilated cardiomyopathy (DCM). In present study, we aim to generate induced pluripotent stem cells derived cardiomyocytes (iPSC-CMs) fro...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Siu, Chung-Wah, Lee, Yee-Ki, Ho, Jenny Chung-Yee, Lai, Wing-Hon, Chan, Yau-Chi, Ng, Kwong-Man, Wong, Lai-Yung, Au, Ka-Wing, Lau, Yee-Man, Zhang, Jinqiu, Lay, Kenneth Weijian, Colman, Alan, Tse, Hung-Fat
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2012
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3560431/
https://ncbi.nlm.nih.gov/pubmed/23362510
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars