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ROCK Inhibition Facilitates the Generation of Human-Induced Pluripotent Stem Cells in a Defined, Feeder-, and Serum-Free System

Human-induced pluripotent stem cells (iPSCs) generated from human adult somatic cells through reprogramming hold great promises for future regenerative medicine. However, exposure of human iPSCs to animal feeder and serum in the process of their generation and maintenance imposes risk of transmittin...

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Main Authors: Lai, Wing-Hon, Ho, Jenny Chung-Yee, Lee, Yee-Ki, Ng, Kwong-Man, Au, Ka-Wing, Chan, Yau-Chi, Lau, Chu-Pak, Tse, Hung-Fat, Siu, Chung-Wah
Formato: Artigo
Idioma:Inglês
Publicado: Mary Ann Liebert, Inc. 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993021/
https://ncbi.nlm.nih.gov/pubmed/20858051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cell.2010.0051
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