Role of NK Cells and Gamma Interferon in Transplacental Passage of Toxoplasma gondii in a Mouse Model of Primary Infection

Protective immunity in mice infected with Toxoplasma gondii is mainly mediated by NK cells, CD4 and CD8 T cells, and type 1 cytokines, such as gamma interferon (IFN-γ). To clarify the roles of NK cells and IFN-γ in protection against primary congenital toxoplasmosis, we used recombination activating...

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Autori principali: Abou-Bacar, Ahmed, Pfaff, Alexander W., Georges, Sophie, Letscher-Bru, Valérie, Filisetti, Denis, Villard, Odile, Antoni, Elisabeth, Klein, Jean-Paul, Candolfi, Ermanno
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
Soggetti:
Fungal and Parasitic Infections
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC356035/
https://ncbi.nlm.nih.gov/pubmed/14977944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.3.1397-1401.2004
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