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Vaccination with Toxoplasma gondii SAG-1 Protein Is Protective against Congenital Toxoplasmosis in BALB/c Mice but Not in CBA/J Mice

We evaluated the effect of vaccination with the SAG1 protein of Toxoplasma gondii against congenital toxoplasmosis in mice with different genetic backgrounds. In BALB/c mice (H-2(d)), vaccination reduced the number of infected fetuses by 50% and was associated with a mixed type 1 and type 2 immunity...

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Detalhes bibliográficos
Main Authors: Letscher-Bru, Valerie, Pfaff, Alexander W., Abou-Bacar, Ahmed, Filisetti, Denis, Antoni, Elisabeth, Villard, Odile, Klein, Jean-Paul, Candolfi, Ermanno
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC219566/
https://ncbi.nlm.nih.gov/pubmed/14573684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.11.6615-6619.2003
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