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A Pharmacological Organization of G Protein-coupled Receptors
Protein classification typically uses structural, sequence, or functional similarity. Here we introduce an orthogonal method that organizes proteins by ligand similarity, focusing here on the class A G protein-coupled receptor (GPCR) protein family. Comparing a ligand-based dendogram to a sequence-b...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3560304/ https://ncbi.nlm.nih.gov/pubmed/23291723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.2324 |
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