Aerosolized Gamma Interferon (IFN-γ) Induces Expression of the Genes Encoding the IFN-γ-Inducible 10-Kilodalton Protein but Not Inducible Nitric Oxide Synthase in the Lung during Tuberculosis

Gamma interferon (IFN-γ) is critical in the immune response against Mycobacterium tuberculosis. In an ongoing trial of aerosol IFN-γ in conjunction with standard drug therapy, we have observed activation of IFN signaling in bronchoalveolar lavage (BAL) cells from tuberculosis (TB) patients. We hypot...

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Main Authors: Raju, Bindu, Hoshino, Yoshihiko, Kuwabara, Kenichi, Belitskaya, Ilana, Prabhakar, Savita, Canova, Antony, Gold, Jeffrey A., Condos, Rany, Pine, Richard I., Brown, Stuart, Rom, William N., Weiden, Michael D.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2004
主題:
Host Response and Inflammation
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC356013/
https://ncbi.nlm.nih.gov/pubmed/14977928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.3.1275-1283.2004
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