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CNLAC1 Is Required for Extrapulmonary Dissemination of Cryptococcus neoformans but Not Pulmonary Persistence

The pathogenic yeast Cryptococcus neoformans produces a laccase enzyme (CNLAC1), which catalyzes the synthesis of melanin in the presence of phenolic compounds. A number of genes have been implicated in the regulation of laccase and melanization, including IPC1, GPA1, MET3, and STE12. Albino mutants...

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Autors principals: Noverr, Mairi C., Williamson, Peter R., Fajardo, Ryan S., Huffnagle, Gary B.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC356011/
https://ncbi.nlm.nih.gov/pubmed/14977977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.3.1693-1699.2004
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