CNLAC1 Is Required for Extrapulmonary Dissemination of Cryptococcus neoformans but Not Pulmonary Persistence

The pathogenic yeast Cryptococcus neoformans produces a laccase enzyme (CNLAC1), which catalyzes the synthesis of melanin in the presence of phenolic compounds. A number of genes have been implicated in the regulation of laccase and melanization, including IPC1, GPA1, MET3, and STE12. Albino mutants...

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Pubblicato in:	Infect Immun
Autori principali:	Noverr, Mairi C., Williamson, Peter R., Fajardo, Ryan S., Huffnagle, Gary B.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2004
Soggetti:	Fungal and Parasitic Infections
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC356011/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14977977/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.72.3.1693-1699.2004
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