Latent Regulatory Potential of Human-Specific Repetitive Elements

At least half of the human genome is derived from repetitive elements, which are often lineage specific and silenced by a variety of genetic and epigenetic mechanisms. Using a transchromosomic mouse strain that transmits an almost complete single copy of human chromosome 21 via the female germline,...

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Autori principali: Ward, Michelle C., Wilson, Michael D., Barbosa-Morais, Nuno L., Schmidt, Dominic, Stark, Rory, Pan, Qun, Schwalie, Petra C., Menon, Suraj, Lukk, Margus, Watt, Stephen, Thybert, David, Kutter, Claudia, Kirschner, Kristina, Flicek, Paul, Blencowe, Benjamin J., Odom, Duncan T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Press 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3560060/
https://ncbi.nlm.nih.gov/pubmed/23246434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.11.013
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