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Role of MyD88 in Diminished Tumor Necrosis Factor Alpha Production by Newborn Mononuclear Cells in Response to Lipopolysaccharide

Human newborns are more susceptible than adults to infection by gram-negative bacteria. We hypothesized that this susceptibility may be associated with a decreased response by leukocytes to lipopolysaccharide (LPS). In this study, we compared LPS-induced secretion of tumor necrosis factor alpha (TNF...

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Udgivet i:Infect Immun
Principais autores: Yan, Sen Rong, Qing, Gefei, Byers, David M., Stadnyk, Andrew W., Al-Hertani, Walla, Bortolussi, Robert
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2004
Fag:
Host Response and Inflammation
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC355999/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14977922/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.72.3.1223-1229.2004
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