Role of MyD88 in Diminished Tumor Necrosis Factor Alpha Production by Newborn Mononuclear Cells in Response to Lipopolysaccharide

Human newborns are more susceptible than adults to infection by gram-negative bacteria. We hypothesized that this susceptibility may be associated with a decreased response by leukocytes to lipopolysaccharide (LPS). In this study, we compared LPS-induced secretion of tumor necrosis factor alpha (TNF...

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Detalhes bibliográficos
Main Authors: Yan, Sen Rong, Qing, Gefei, Byers, David M., Stadnyk, Andrew W., Al-Hertani, Walla, Bortolussi, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC355999/
https://ncbi.nlm.nih.gov/pubmed/14977922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.3.1223-1229.2004
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