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The Legionella pneumophila PilT Homologue DotB Exhibits ATPase Activity That Is Critical for Intracellular Growth

The ability of Legionella pneumophila to grow and cause disease in the host is completely dependent on a type IV secretion system known as the Dot/Icm complex. This membrane-spanning apparatus translocates effector molecules into host cells in a process that is poorly understood but that is known to...

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Autori principali: Sexton, Jessica A., Pinkner, Jerome S., Roth, Robyn, Heuser, John E., Hultgren, Scott J., Vogel, Joseph P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC355965/
https://ncbi.nlm.nih.gov/pubmed/14996796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.186.6.1658-1666.2004
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