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On Combining Reference Data to Improve Imputation Accuracy
Genotype imputation is an important tool in human genetics studies, which uses reference sets with known genotypes and prior knowledge on linkage disequilibrium and recombination rates to infer un-typed alleles for human genetic variations at a low cost. The reference sets used by current imputation...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3559437/ https://ncbi.nlm.nih.gov/pubmed/23383238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055600 |
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