Integrating High-Content Imaging and Chemical Genetics to Probe Host Cellular Pathways Critical for Yersinia Pestis Infection

The molecular machinery that regulates the entry and survival of Yersinia pestis in host macrophages is poorly understood. Here, we report the development of automated high-content imaging assays to quantitate the internalization of virulent Y. pestis CO92 by macrophages and the subsequent activatio...

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Detalhes bibliográficos
Main Authors: Kota, Krishna P., Eaton, Brett, Lane, Douglas, Ulrich, Melanie, Ulrich, Ricky, Peyser, Brian D., Robinson, Camenzind G., Jaissle, James G., Pegoraro, Gianluca, Bavari, Sina, Panchal, Rekha G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3559335/
https://ncbi.nlm.nih.gov/pubmed/23383093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055167
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