Internalization of Locked Nucleic Acids/DNA Hybrid Oligomers into Escherichia coli

Delivery inside the cells is essential for practical application of antisense technologies. The hybrid locked nucleic acid (LNA)/DNA CAAGTACTGTTCCACCA (LNA residues are underlined) was labeled by conjugation to Alexa Fluor 488 (fLNA/DNA) and tested to determine its ability to penetrate Escherichia c...

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Détails bibliographiques
Auteurs principaux: Traglia, German M., Sala, Carol Davies, Fuxman Bass, Juan I., Soler-Bistué, Alfonso J.C., Zorreguieta, Angeles, Ramírez, María Soledad, Tolmasky, Marcelo E.
Format: Artigo
Langue:Inglês
Publié: Mary Ann Liebert, Inc. 2012
Sujets:
Brief Reports
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3559211/
https://ncbi.nlm.nih.gov/pubmed/23515318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/biores.2012.0257
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