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RGS12 Is Essential for RANKL-Evoked Signaling for Terminal Differentiation of Osteoclasts In Vitro

How RANKL evokes [Ca(2+)](i) oscillations and leads to osteoclast differentiation is unclear. We identified a new signaling protein, RGS12, and found that RGS12 is essential for [Ca(2+)](i) oscillations and osteoclast differentiation induced by RANKL. RGS12 may play a critical role in the RANKL-evok...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yang, Shuying, Li, Yi-Ping
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3559086/
https://ncbi.nlm.nih.gov/pubmed/17042716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1359/jbmr.061007
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