Follicular Helper NKT Cells Induce Limited B Cell Responses and Germinal Center Formation in the Absence of CD4(+) T Cell Help

B cells require MHC class II (MHC II)-restricted cognate help and CD40 engagement by CD4(+) T follicular helper (T(FH)) cells to form germinal centers and long-lasting Ab responses. Invariant NKT (iNKT) cells are innate-like lymphocytes that jumpstart the adaptive immune response when activated by t...

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Hlavní autoři: Tonti, Elena, Fedeli, Maya, Napolitano, Anna, Iannacone, Matteo, von Andrian, Ulrich H., Guidotti, Luca G., Abrignani, Sergio, Casorati, Giulia, Dellabona, Paolo
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3559029/
https://ncbi.nlm.nih.gov/pubmed/22379027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103501
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