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Voltage-sensing domain of voltage-gated proton channel Hv1 shares mechanism of block with pore domains
Voltage-gated sodium, potassium, and calcium channels are made of a pore domain (PD) controlled by four voltage-sensing domains (VSDs). The PD contains the ion permeation pathway and the activation gate located on the intracellular side of the membrane. A large number of small molecules are known to...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3559007/ https://ncbi.nlm.nih.gov/pubmed/23352164 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2012.11.013 |
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