Long-term safety of mepolizumab for the treatment of hypereosinophilic syndromes

BACKGROUND: Hypereosinophilic syndromes (HES) are chronic disorders that require long-term therapy to suppress eosinophilia and clinical manifestations. Corticosteroids are usually effective, yet many patients become corticosteroid-refractory or develop corticosteroid toxicity. Mepolizumab, a humani...

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Detalhes bibliográficos
Main Authors: Roufosse, Florence E, Kahn, Jean-Emmanuel, Gleich, Gerald J, Schwartz, Lawrence B, Singh, Anish D, Rosenwasser, Lanny J, Denburg, Judah A, Ring, Johannes, Rothenberg, Marc E, Sheikh, Javed, Haig, Ann E, Mallett, Stephen A, Templeton, Deborah N, Ortega, Hector G, Klion, Amy D
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3558744/
https://ncbi.nlm.nih.gov/pubmed/23040887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2012.07.055
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