Mepolizumab as a corticosteroid-sparing agent in lymphocytic variant hypereosinophilic syndrome

BACKGROUND: Mepolizumab, a monoclonal anti-interleukin-5 (IL-5) antibody, is an effective corticosteroid-sparing agent for patients with F/P-negative hypereosinophilic syndrome. Lymphocytic variant hypereosinophilic syndrome (L-HES) is characterized by marked overproduction of IL-5 by dysregulated T...

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Detalhes bibliográficos
Main Authors: Roufosse, Florence, de Lavareille, Aurore, Schandené, Liliane, Cogan, Elie, Georgelas, Ann, Wagner, Lori, Xi, Liqiang, Raffeld, Mark, Goldman, Michel, Gleich, Gerald J., Klion, Amy
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950246/
https://ncbi.nlm.nih.gov/pubmed/20810155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2010.06.049
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