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Bone vascularization and trabecular bone formation are mediated by PKBalpha/Akt1 in a gene dosage dependent manner: In vivo and ex vivo MRI
PKBalpha/Akt1, a protein kinase, is a major mediator of angiogenic signaling. The purpose of this study was to determine the role of PKBalpha/Akt1 in bone vascularization and development. For that aim, macromolecular dynamic contrast enhanced MRI (DCE-MRI) was applied to examine in vivo vascular cha...
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| Hoofdauteurs: | , , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2010
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3558735/ https://ncbi.nlm.nih.gov/pubmed/20572141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.22395 |
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