Efficient production of foot-and-mouth disease virus empty capsids in insect cells following down regulation of 3C protease activity

Foot-and-mouth disease virus (FMDV) is a significant economically and distributed globally pathogen of Artiodactyla. Current vaccines are chemically inactivated whole virus particles that require large-scale virus growth in strict bio-containment with the associated risks of accidental release or in...

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Autori principali: Porta, Claudine, Xu, Xiaodong, Loureiro, Silvia, Paramasivam, Saravanan, Ren, Junyuan, Al-Khalil, Tara, Burman, Alison, Jackson, Terry, Belsham, Graham J., Curry, Stephen, Lomonossoff, George P., Parida, Satya, Paton, David, Li, Yanmin, Wilsden, Ginette, Ferris, Nigel, Owens, Ray, Kotecha, Abhay, Fry, Elizabeth, Stuart, David I., Charleston, Bryan, Jones, Ian M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier/North-Holland Biomedical Press 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3558679/
https://ncbi.nlm.nih.gov/pubmed/23174161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jviromet.2012.11.011
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