Efficient production of foot-and-mouth disease virus empty capsids in insect cells following down regulation of 3C protease activity

Foot-and-mouth disease virus (FMDV) is a significant economically and distributed globally pathogen of Artiodactyla. Current vaccines are chemically inactivated whole virus particles that require large-scale virus growth in strict bio-containment with the associated risks of accidental release or in...

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Main Authors: Porta, Claudine, Xu, Xiaodong, Loureiro, Silvia, Paramasivam, Saravanan, Ren, Junyuan, Al-Khalil, Tara, Burman, Alison, Jackson, Terry, Belsham, Graham J., Curry, Stephen, Lomonossoff, George P., Parida, Satya, Paton, David, Li, Yanmin, Wilsden, Ginette, Ferris, Nigel, Owens, Ray, Kotecha, Abhay, Fry, Elizabeth, Stuart, David I., Charleston, Bryan, Jones, Ian M.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier/North-Holland Biomedical Press 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3558679/
https://ncbi.nlm.nih.gov/pubmed/23174161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jviromet.2012.11.011
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