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Reversible RNA adenosine methylation in biological regulation

N(6)-methyladenosine (m(6)A) is a ubiquitous modification in messenger RNA (mRNA) and other RNAs across most eukaryotes. For many years, however, the exact functions of m(6)A were not clearly understood. The discovery that the fat mass and obesity associated protein (FTO) is an m(6)A demethylase ind...

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Detalhes bibliográficos
Main Authors: Jia, Guifang, Fu, Ye, He, Chuan
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3558665/
https://ncbi.nlm.nih.gov/pubmed/23218460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2012.11.003
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