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The Role of Glycoprotein 96 in the Persistent Inflammation of Rheumatoid Arthritis

The 96-kDa glycoprotein (gp96) is an endoplasmic reticulum (ER) resident molecular chaperone. Under physiologic conditions, gp96 facilitates the transport of toll-like receptors (TLRs) to cell or endosomal membranes. Under pathologic circumstances such as rheumatoid arthritis, gp96 translocates to t...

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Autors principals: Huang, Qi-Quan, Pope, Richard M.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3558611/
https://ncbi.nlm.nih.gov/pubmed/23257071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2012.12.008
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