Bidirectional Signaling Links the Abelson Kinases to the Platelet-Derived Growth Factor Receptor

The c-Abl nonreceptor tyrosine kinase is activated by growth factor signals such as the platelet-derived growth factor (PDGF) and functions downstream of the PDGF-β receptor (PDGFR) to mediate biological processes such as membrane ruffling, mitogenesis, and chemotaxis. Here, we show that the related...

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Bibliographic Details
Main Authors: Plattner, Rina, Koleske, Anthony J., Kazlauskas, Andrius, Pendergast, Ann Marie
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Cell Growth and Development
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC355852/
https://ncbi.nlm.nih.gov/pubmed/14993293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.6.2573-2583.2004
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