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Membrane-displayed somatostatin activates somatostatin receptor subtype-2 heterologously produced in Saccharomyces cerevisiae

The G-protein-coupled receptor (GPCR) superfamily, which includes somatostatin receptors (SSTRs), is one of the most important drug targets in the pharmaceutical industry. The yeast Saccharomyces cerevisiae is an attractive host for the ligand screening of human GPCRs. Here, we demonstrate the utili...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Hara, Keisuke, Shigemori, Tomohiro, Kuroda, Kouichi, Ueda, Mitsuyoshi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3558460/
https://ncbi.nlm.nih.gov/pubmed/23193953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2191-0855-2-63
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