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Membrane-displayed somatostatin activates somatostatin receptor subtype-2 heterologously produced in Saccharomyces cerevisiae

The G-protein-coupled receptor (GPCR) superfamily, which includes somatostatin receptors (SSTRs), is one of the most important drug targets in the pharmaceutical industry. The yeast Saccharomyces cerevisiae is an attractive host for the ligand screening of human GPCRs. Here, we demonstrate the utili...

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Detalles Bibliográficos
Main Authors: Hara, Keisuke, Shigemori, Tomohiro, Kuroda, Kouichi, Ueda, Mitsuyoshi
Formato: Artigo
Idioma:Inglês
Publicado: Springer 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3558460/
https://ncbi.nlm.nih.gov/pubmed/23193953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2191-0855-2-63
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