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Peripheral Blood Monocyte Sirt1 Expression Is Reduced in Patients with Coronary Artery Disease

BACKGROUND: Inflammation plays a key role in atherosclerosis. Sirt1 regulates transcription factors involved in inflammatory processes and blunts atherosclerosis in mice. However, its role in humans remains to be defined. This study was therefore designed to investigate the role of Sirt1 in the deve...

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Detalhes bibliográficos
Main Authors: Breitenstein, Alexander, Wyss, Christophe A., Spescha, Remo D., Franzeck, Fabian C., Hof, Danielle, Riwanto, Meliana, Hasun, Matthias, Akhmedov, Alexander, von Eckardstein, Arnold, Maier, Willibald, Landmesser, Ulf, Lüscher, Thomas F., Camici, Giovanni G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3558418/
https://ncbi.nlm.nih.gov/pubmed/23382833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053106
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