Increased Numbers of B-1 Cells and Enhanced Responses against TI-2 Antigen in Mice Lacking APS, an Adaptor Molecule Containing PH and SH2 Domains

APS (adaptor molecule containing PH and SH2 domains) is an intracellular adaptor protein that forms an adaptor family along with Lnk and SH2-B. While experiments using cultured cell lines have demonstrated that APS is phosphorylated in response to various stimuli, its in vivo functions remain unclea...

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Autors principals: Iseki, Masanori, Kubo, Chiyomi, Kwon, Sang-Mo, Yamaguchi, Akiko, Kataoka, Yuki, Yoshida, Nobuaki, Takatsu, Kiyoshi, Takaki, Satoshi
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
Matèries:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC355841/
https://ncbi.nlm.nih.gov/pubmed/14993264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.6.2243-2250.2004
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