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SRC Proximal and Core Promoter Elements Dictate TAF1 Dependence and Transcriptional Repression by Histone Deacetylase Inhibitors

Histone deacetylase inhibitors (HDIs) induce cell cycle arrest, differentiation, or apoptosis in numerous cancer cell types both in vivo and in vitro. These dramatic effects are the result of a specific reprogramming of gene expression. However, the mechanism by which these agents activate the trans...

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Autori principali: Dehm, Scott M., Hilton, Traci L., Wang, Edith H., Bonham, Keith
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC355838/
https://ncbi.nlm.nih.gov/pubmed/14993269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.6.2296-2307.2004
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