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An array CGH based genomic instability index (G2I) is predictive of clinical outcome in breast cancer and reveals a subset of tumors without lymph node involvement but with poor prognosis

BACKGROUND: Despite entering complete remission after primary treatment, a substantial proportion of patients with early stage breast cancer will develop metastases. Prediction of such an outcome remains challenging despite the clinical use of several prognostic parameters. Several reports indicate...

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Autors principals: Bonnet, Françoise, Guedj, Mickael, Jones, Natalie, Sfar, Sana, Brouste, Véronique, Elarouci, Nabila, Banneau, Guillaume, Orsetti, Béatrice, Primois, Charlotte, de Lara, Christine Tunon, Debled, Marc, de Mascarel, Isabelle, Theillet, Charles, Sévenet, Nicolas, de Reynies, Aurélien, MacGrogan, Gaëtan, Longy, Michel
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3558323/
https://ncbi.nlm.nih.gov/pubmed/23186559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-5-54
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