Human Tissue Plasminogen Activator Expression in Escherichia coli using Cytoplasmic and Periplasmic Cumulative Power

Tissue plasminogen activator (tPA) is a serine protease, which is composed of five distinct structural domains with 17 disulfide bonds, representing a model of high-disulfide proteins in human body. One of the most important limitations for high yield heterologous protein production in Escherichia c...

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Main Authors: Majidzadeh-A, Keivan, Mahboudi, Fereidoun, Hemayatkar, Mahdi, Davami, Fatemeh, Barkhordary, Farzaneh, Adeli, Ahmad, Soleimani, Mohammad, Davoudi, Noushin, Khalaj, Vahid
Format: Artigo
Jezik:Inglês
Izdano: Avicenna Research Institute 2010
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Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3558155/
https://ncbi.nlm.nih.gov/pubmed/23408156
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