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Locomotor Activity in Mice During Chronic Treatment With Caffeine and Withdrawal

Chronic ingestion of caffeine by mice caused a marked reduction in locomotor exploratory activity. At least 4 days of withdrawal were required to restore activity to normal levels. Stimulatory effects of injected caffeine were lower in chronically treated mice and the biphasic dose-response (stimula...

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Detalhes bibliográficos
Main Authors: NIKODIJEVIĆ, OLGA, JACOBSON, KENNETH A., DALY, JOHN W.
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557839/
https://ncbi.nlm.nih.gov/pubmed/7679219
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