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Antigen loss and tumor-mediated immunosuppression facilitate tumor recurrence

While tumor immunotherapy has seen notable success in recent years, mechanisms that tumors utilize to escape immune responses have provided significant hurdles to maximal clinical benefit. Escape mechanisms such as antigen loss, decreased MHC expression, as well as tumor-mediated suppressive effects...

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Detalhes bibliográficos
Main Authors: Olson, Brian M, McNeel, Douglas G
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557828/
https://ncbi.nlm.nih.gov/pubmed/23249231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/erv.12.107
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