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Antigen loss and tumor-mediated immunosuppression facilitate tumor recurrence

While tumor immunotherapy has seen notable success in recent years, mechanisms that tumors utilize to escape immune responses have provided significant hurdles to maximal clinical benefit. Escape mechanisms such as antigen loss, decreased MHC expression, as well as tumor-mediated suppressive effects...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Olson, Brian M, McNeel, Douglas G
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557828/
https://ncbi.nlm.nih.gov/pubmed/23249231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/erv.12.107
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