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CD8+ T cells specific for the androgen receptor are common in patients with prostate cancer and are able to lyse prostate tumor cells

The androgen receptor (AR) is a hormone receptor that plays a critical role in prostate cancer, and depletion of its ligand has long been the cornerstone of treatment for metastatic disease. Here, we evaluate the AR ligand-binding domain (LBD) as an immunological target, seeking to identify HLA-A2-r...

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Bibliografische gegevens
Hoofdauteurs: Olson, Brian M., McNeel, Douglas G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319721/
https://ncbi.nlm.nih.gov/pubmed/21350948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-011-0987-5
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