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Signal Activation and Inactivation by the Gα Helical Domain: A Long-Neglected Partner in G Protein Signaling
Heterotrimeric guanine nucleotide–binding proteins (G proteins) are positioned at the top of many signal transduction pathways. The G protein α subunit is composed of two domains, one that resembles Ras and another that is composed entirely of α helices. Historically, most attention has focused on t...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3557789/ https://ncbi.nlm.nih.gov/pubmed/22649098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2003013 |
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