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Signal Activation and Inactivation by the Gα Helical Domain: A Long-Neglected Partner in G Protein Signaling

Heterotrimeric guanine nucleotide–binding proteins (G proteins) are positioned at the top of many signal transduction pathways. The G protein α subunit is composed of two domains, one that resembles Ras and another that is composed entirely of α helices. Historically, most attention has focused on t...

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Autori principali: Dohlman, Henrik G., Jones, Janice C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557789/
https://ncbi.nlm.nih.gov/pubmed/22649098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2003013
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