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SMRT-mediated co-shuttling enables export of class IIa HDACs independent of their CaM kinase phosphorylation sites
The Class IIa histone deacetylases (HDAC)4 and HDAC5 play a role in neuronal survival and behavioral adaptation in the CNS. Phosphorylation at 2/3 N-terminal sites promote their nuclear export. We investigated whether non-canonical signaling routes to Class IIa HDAC export exist because of their ass...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Blackwell Publishing Ltd
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3557716/ https://ncbi.nlm.nih.gov/pubmed/23083128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12058 |
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