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Blockade of estrogen by hormonal contraceptives impairs fear extinction in female rats and women

BACKGROUND: Fear extinction is a laboratory model of fear inhibition and is the basis of exposure therapy for anxiety disorders. Emerging evidence from naturally cycling female rodents and women indicates that estrogens are necessary to the consolidation of fear extinction. Hormonal contraceptives (...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Graham, Bronwyn M, Milad, Mohammed R
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557577/
https://ncbi.nlm.nih.gov/pubmed/23158459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2012.09.018
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