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Blockade of estrogen by hormonal contraceptives impairs fear extinction in female rats and women

BACKGROUND: Fear extinction is a laboratory model of fear inhibition and is the basis of exposure therapy for anxiety disorders. Emerging evidence from naturally cycling female rodents and women indicates that estrogens are necessary to the consolidation of fear extinction. Hormonal contraceptives (...

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Detalhes bibliográficos
Main Authors: Graham, Bronwyn M, Milad, Mohammed R
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557577/
https://ncbi.nlm.nih.gov/pubmed/23158459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2012.09.018
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