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Increased dietary intake of vitamin A promotes aortic valve calcification in vivo
OBJECTIVE: Calcific aortic valve disease (CAVD) is a major public health problem with no effective treatment available other than surgery. We previously showed that mature heart valves calcify in response to retinoic acid (RA) treatment through downregulation of the SRY-transcription factor Sox9. In...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3557503/ https://ncbi.nlm.nih.gov/pubmed/23202364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.300388 |
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