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The endocrine stress response is linked to one specific locus on chromosome 3 in a mouse model based on extremes in trait anxiety

BACKGROUND: The hypothalamic-pituitary-adrenal (HPA) axis is essential to control physiological stress responses in mammals. Its dysfunction is related to several mental disorders, including anxiety and depression. The aim of this study was to identify genetic loci underlying the endocrine regulatio...

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Autors principals: Gonik, Mariya, Frank, Elisabeth, Keßler, Melanie S, Czamara, Darina, Bunck, Mirjam, Yen, Yi-Chun, Pütz, Benno, Holsboer, Florian, Bettecken, Thomas, Landgraf, Rainer, Müller-Myhsok, Bertram, Touma, Chadi, Czibere, Ludwig
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557225/
https://ncbi.nlm.nih.gov/pubmed/23114097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-579
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