Lymphocyte-derived ACh regulates local innate but not adaptive immunity

Appropriate control of immune responses is a critical determinant of health. Here, we show that choline acetyltransferase (ChAT) is expressed and ACh is produced by B cells and other immune cells that have an impact on innate immunity. ChAT expression occurs in mucosal-associated lymph tissue, subse...

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Autors principals: Reardon, Colin, Duncan, Gordon S., Brüstle, Anne, Brenner, Dirk, Tusche, Michael W., Olofsson, Peder S., Rosas-Ballina, Mauricio, Tracey, Kevin J., Mak, Tak W.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2013
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557089/
https://ncbi.nlm.nih.gov/pubmed/23297238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1221655110
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