Insights into the regulation of the human COP9 signalosome catalytic subunit, CSN5/Jab1

The COP9 (Constitutive photomorphogenesis 9) signalosome (CSN), a large multiprotein complex that resembles the 19S lid of the 26S proteasome, plays a central role in the regulation of the E3-cullin RING ubiquitin ligases (CRLs). The catalytic activity of the CSN complex, carried by subunit 5 (CSN5/...

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Autors principals: Echalier, Aude, Pan, Yunbao, Birol, Melissa, Tavernier, Nicolas, Pintard, Lionel, Hoh, François, Ebel, Christine, Galophe, Nathalie, Claret, François X., Dumas, Christian
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2013
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557056/
https://ncbi.nlm.nih.gov/pubmed/23288897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1209345110
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