Rapid sensing of circulating ghrelin by hypothalamic appetite-modifying neurons

To maintain homeostasis, hypothalamic neurons in the arcuate nucleus must dynamically sense and integrate a multitude of peripheral signals. Blood-borne molecules must therefore be able to circumvent the tightly sealed vasculature of the blood–brain barrier to rapidly access their target neurons. Ho...

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Main Authors: Schaeffer, Marie, Langlet, Fanny, Lafont, Chrystel, Molino, François, Hodson, David J., Roux, Thomas, Lamarque, Laurent, Verdié, Pascal, Bourrier, Emmanuel, Dehouck, Bénédicte, Banères, Jean-Louis, Martinez, Jean, Méry, Pierre-François, Marie, Jacky, Trinquet, Eric, Fehrentz, Jean-Alain, Prévot, Vincent, Mollard, Patrice
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2013
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557016/
https://ncbi.nlm.nih.gov/pubmed/23297228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1212137110
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