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Rolling back neutrophil adhesion

Neutrophils and other cells secrete pentraxin 3, which promotes innate immunity by binding to pathogens and activating complement. New work shows that pentraxin 3 also limits neutrophil recruitment by inhibiting rolling on P-selectin in inflamed venules.

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Bibliographic Details
Main Author: McEver, Rodger P.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556925/
https://ncbi.nlm.nih.gov/pubmed/20300135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni0410-282
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